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 • DesLoratadine

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DesLoratadine

DesLoratadine is used for relief of symptoms in allergic rhinitis. The allergy is a hypersensitivity reaction of the immune system to harmless substances such as pollen, pet dander and more. In an attempt to defeat the supposed enemies, large quantities are produced of inflammatory mediators – including the tissue hormone histamine and signal substances from the group of leukotrienes and cytokines. These messengers resolve inflammation and are ultimately for the complaints verantwortlich.Histamin plays a key role: it coupled to specific binding sites of cells and triggers various reactions: the fine blood vessels are expanded, there will be redness and swelling – pain and inflammations occur. DesLoratadine is an H1 antihistamine: It blocks the tissue specific binding sites for histamine, the histamine H1 receptors. Histamine is still released, but no longer finds it sufficient free binding sites in order to exert its effect. Presumably, but also reduces the DesLoratadine release of histamine and leukotrienes, and so has additional anti-inflammatory properties. DesLoratadine is a further development of the drug Loratadine: Because it is about twice as effective, you come out with a lesser amount of drug per tablet. DesLoratadine improves typical allergy symptoms such as redness and itching, watery eyes, swollen nasal membranes, sneezing and nasal discharge. The drug does not have the soothing and dampening effect of many other antihistamines – he does not get into the brain, but acts only in the rest of the body.

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