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Diltiazem is used to treat heart and circulatory diseases. The blood pressure is constantly updated by a complicated system of different messenger substances the body’s needs. When sleeping is as significantly lower blood pressure needed to provide the tissue with nutrients and oxygen, as in sports. The mineral calcium has an important role in this control system: It controls the activity of muscle cells that surround blood vessels. Special channels in the cell wall of muscle cells can flow to certain signals calcium into the cells. Inside the cell, the calcium then the tension of the muscle cells triggers. Through the tense muscles, the vessels constrict and blood pressure rises. Diltiazem is a calcium antagonist, also known as calcium channel blockers. It works by blocking these channels in the wall of the vascular muscles and prevents calcium passes into the muscle cells. The muscle cells relax, and the blood vessels are expanded. This circulation is improved, and blood pressure drops. Diltiazem extended those blood vessels that supply the heart with oxygen – it thus facilitates the cardiac work. Narrowed or tensed blood vessels to the heart can be the cause of chest pain in addition: In certain forms of heart Enge () causes Diltiazem therefore also an improvement in symptoms. Additionally, Diltiazem acts directly on the heart muscle: It blocked there calcium channels of the muscle fibers of the heart – the heart beats more slowly, and the impact force decreases. This also decreases the blood pressure, and is consumed less oxygen. Since Diltiazem slows the pace of the heart beat, it can also affect cardiac arrhythmias favorable if they are connected to too rapid heartbeat.