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 • Fexofenadine

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Fexofenadine

Fexofenadine is used in allergic rhinitis and allergic skin diseases. The allergy is a hypersensitivity reaction of the immune system to harmless substances such as pollen, pet dander and more. In an attempt to defeat the supposed enemies, large quantities are produced of inflammatory mediators – including the tissue hormone histamine and signal substances from the group of leukotrienes and cytokines. These messengers trigger inflammation and are ultimately responsible for the complaints. Histamine plays a key role: it coupled to at specific binding sites of cells and triggers various reactions: the fine blood vessels are expanded, there will be redness and swelling – pain and inflammation occur. Fexofenadine is an antihistamine H1: It blocks the tissue specific binding sites for histamine, the histamine H1 receptors. Histamine is still released, but no longer finds it sufficient free binding sites in order to exert its effect. Fexofenadine but also reduces the release of histamine and leukotrienes, and so has additional anti-inflammatory properties. Fexofenadine improves typical allergy symptoms such as redness and itching, swollen nasal membranes, sneezing and nasal discharge. The drug does not have the soothing, steaming effect of many other antihistamines -. He does not get into the brain, but acts only in the rest of the body

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