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The active ingredient Loratadine is one of the most important remedies for allergies. As a so-called second-generation antihistamine of it does – unlike its predecessors – with the same effectiveness practically not tired. Due to the good tolerability of the active ingredient also applies to pregnant and lactating women as a treatment of choice for allergic reactions. Here you can read everything about Loratadine.
How Loratadine acts
An allergic reaction is a hypersensitivity reaction of the immune system. In case of contact with a really innocuous allergy triggers (allergens such as pollen, house dust or animal hair) comes suddenly to an excessive release of the neurotransmitter histamine to the the body as ‘foreign’ recognized allergen to fight. Binds histamine in the wake of its docking site (receptor), it comes to the typical symptoms of allergy such as an increased tissue perfusion (redness, swelling, hives), watery eyes, runny nose up to the cramping of the muscles of the airways (bronchospasm) .
As a so-called anti-histamine inhibits Loratadine by blocking the histamine receptor (H 1receptor) the effects of histamine and thus relieves the symptoms of an allergic reaction.
Up, reduction and elimination of Loratadine
After recording via the mouth (orally), the active ingredient is rapidly and completely absorbed from the intestine into the blood. It is distributed in the body and is then metabolized in the liver. The degradation products are then excreted by the kidneys.
When to use Loratadine?
Among the areas of application (indications) of Loratadine include:
- allergic rhinitis-related (allergic rhinitis) such as
- allergic skin reactions such as hives (or urticaria)
How is Loratadine applied
The active ingredient Loratadine is usually applied in the form of tablets. Normally, allergy tablets should rather be taken in the evening, because they make the most tired. For drugs with Loratadine but this is practically not the case.
The Loratadine dosage is usually ten milligrams daily. Infants and people with liver dysfunction receive a reduced dose.
The tablets may be taken with or without food (best with a big glass of tap water).
What are the side effects of Loratadine?
Often, that is, at one to ten percent of those treated, Loratadine may cause side effects such as fatigue and cause.
On rare occasions by the ingestion of the drug to an increased appetite and gastrointestinal complaints.
What should be considered when taking Loratadine?
in patients with severe hepatic impairment should drugs with Loratadine be used with caution, because it can come by a delayed degradation to an increased effect.
Unlike other allergy means is a reinforcing effect when co-administered with alcohol unknown.
One interaction with other drugs, which leads to increased side effects, is also not known.
Driving and using machines
Loratadine may cause in rare cases, as a side effect fatigue. Therefore, it should be taken just at the beginning of treatment to the individual response to the drug. If you are unsure should be decided in conjunction with a doctor if you actively participate in traffic or permitted to operate heavy machinery.
The active ingredient Loratadine should be used from the age of two years (or from a body weight of 30 kilograms). Children who are younger or lighter should consult with an allergic reaction always a doctor.
Pregnancy and lactation
The effect of Loratadine on unborn babies and is very well studied. Under the administration have been found no harmful effects, even though the drug is excreted in human breast milk. Therefore, drugs with Loratadine are considered drugs of choice against allergic reactions in pregnant and breastfeeding women.
How to obtain drugs with Loratadine
drug Loratadine are considered very well tolerated and are therefore suitable for self-medication. You get them for this reason can be sold in pharmacies.
How long Loratadine is known?
Loratadine is a relatively new drug. As a so-called second-generation antihistamine of its mode of action is much more specific than that of its predecessors and has significantly fewer side effects with equal effectiveness on.
Unlike other allergy medications (such as newer) makes Loratadine by its very specific attack practically not tired, which is a clear advantage over the other members of this drug class.
More interesting facts about Loratadine
medicines with Loratadine also suppress allergic skin reactions. Therefore, they should always be discontinued at least two days before an allergy skin test. This is a test, be applied directly to the skin with the allergens to find out on which the allergen Treated responding (certain pollens, house dust, animal dander, etc.). If you do not settle the allergy pills with Loratadine before, it could be that a really positive test falsely negative, an existing allergy is therefore not recognized.